In Vitro Diagnostic Industry in China - POCT IV

4. Biochip Technology

Biochips enable the accurate, rapid, and high-throughput detection of DNA, RNA, polypeptides, proteins, cells, tissues, and other biological components, with great advantages in disease screening and early diagnosis. Biochip research has become a hot topic in laboratory medicine. It allows many items to be simultaneously measured on a small chip, thereby significantly improving the efficiency of analysis. Currently, biochips can be divided into gene, protein, or cell chips, as well as the lab-on-a-chip. They have the advantages of high sensitivity, short analysis time, and the ability to analyze many items simultaneously. Many analysis steps involved in life science research use microelectronics, micromechanics, physical technology, sensor technology, and computer technology to realize continuous, integrated, and miniaturized sample detection and analysis processes. They also have obvious advantages for the detection of infectious diseases, such as the integration of a portable low-cost customized detector and a novel detection platform with microporous array biochips.

5. Chemiluminescence Immunoassay Technology

Chemiluminescence immunoassays use specific immune responses. Combined with the high sensitivity of chemiluminescence, it has the advantages of high sensitivity, strong specificity, good precision, and a wide linear range. This has become an important non-isotope-labeled immunoassay method. This traditional test method has been greatly expanded and enriched by the miniaturization and portability concepts of POCT. Chemiluminescence POCTs can be used in some clinical application fields that demand high accuracy and quick turnaround, such as hospital ICU, emergency department, cardiology department, and chest pain centers. Furthermore, it can also be used in small and medium-sized hospitals, social health centers, and clinics to improve the efficiency of diagnosis. Chemiluminescent POCT products are well suited for use in the initial diagnosis of severe inflammatory infections, cardiovascular and cerebrovascular diseases, and rapidly monitoring changes in the clinical course. Domestic POCT manufacturers have also successively introduced chemiluminescent POCT instruments and reagents, which will become the key development direction of POCT detection technology in the future.

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