In Vitro Diagnostic Industry in China - Molecular Diagnosis Analyzers and Reagents VII

1.3 Automatic Nucleic Acid Extractor Paraffin Sample

With a large number of tumor-targeted drugs on the market, companion diagnosis is increasingly used in the process of tumor treatment. The results of using tissue samples for tumor companion diagnosis are more accurate than selecting plasma-free DNA (cell-free DNA, cfDNA). Formalin-fixed paraffin-embedded (FFPE) tissue samples are the most commonly used type of tissue samples in pathology, so the nucleic acid extraction of FFPE samples has become a necessary step for the companion diagnosis of most tumors. However, it is more difficult to realize an automatic extraction of nucleic acid from FFPE samples than that of liquid samples, and most FFPE samples need to undergo manual dewaxing, digestion, and cross-linking steps before subsequent automatic extraction. Liferiver iMagNext automatic nucleic acid extractor (Record No.: H.M.X.B. 20,190,065) can automatically complete the steps of sample dewaxing, digestion, and cross-linking in the instrument, and the whole process takes only 2.5h.

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